In-Vivo Lens Shaping Proof of Concept

Purpose: Evaluate the feasibility to create a diopter change inide an acrylic IOL using a femtosecond laser while keeping a good MTF.
Method: Shaping a suitable lens design of a 4D RIS lens into a standard hydrophobic IOL. The measurements before and after are performed using the PMTF from Lambda X.
Results: The original IOL measured 20.6D with an MTF of 0.6, after RIS the IOL measured 24.6D with an MTF of 0.56.
Conclusion: The RIS technology can be used to change an existing IOL.

3mm Aperture Measurement

Measurement Result. Before the refractive index treatment the intraocular lens measured 20.6 diopter with an MTF of 0.6 for the 100 linepair measurement.

4.5mm Aperture Measurement

Measurement Results for the 4.5mm aperture measurement show an improved MTF after shaping.

Diffractive Multifocal to Monofocal

Purpose: Evaluate the possibility to change a diffractive multifocal into a monofocal IOL
Method: A suitable lens design was created to match the diffractive power and energy split of the diffractive multifocal IOL.
Results: The original IOL measured 20.85D with an add of 3.58D and a MTF of 0.37 and 0.26, after RIS shaping the IOL measured as a monofocal IOL at 21.04D with an MTF of 0.57.
Conclusion: The RIS technology can be used to change a diffractive multifocal into a monofocal IOL.

Before RIS

Measurement Result. Before the refractive index treatment the lens measured a near and a far peak and therefore was multifocal.

After RIS

Measurement Result. After the refractive index treatment the lens measured only a far peak.

Monofocal to Multifocal

Purpose: Evaluate the possibility to add multifocality to a monofocal IOL
Method: A suitable lens design was created a multifocality with an add of 3.6D and a 50/50 split.
Results: The IOL before RIS treatment measured 5.27D with an MTF of 0.53 for the 100lp/mm measurement. After RIS treatment the IOL measured two foci at 5.25D and 8.83D with 51/49 split.
Conclusion: The RIS technology can be used to add multifocality to monofocal IOL.

Before RIS

Measurement result. Before the refractive index treatment the through focus curve showed only a far peak.

After RIS

Measurement result. After the refractive index treatment the through focus curve showed a far and a near peak.

Repeatability

The next example shows the repeatability of the process. All lenses have been shaped in sequence.

A graph displays 9 measurement results which all measure very close to a -2 diopter change. The horizontal axis shows the measurement for each of the 9 intraocular lens measurements and the vertical axis shows a diopter change range between 0 and -4 diopter.